
Amelioration of Inflammation and Metabolic Blockage in GALC Deficient Mice After Enzyme Replacement Therapy via ...
Introduction Krabbe disease (KD) is caused by a deficiency in the lysosomal enzyme galactosylceramidase (GALC), resulting in the toxic accumulation of galactosylceramide, and galactosylsphingosine (also known as psychosine), primarily in lysosomes and …